Glycerol, amino acids and free fatty acids will have what effect on the hypothalamus gland?

The hypothalamus plays a crucial role in regulating hunger and satiety, influencing food intake based on energy levels in the body. Glycerol, amino acids, and free fatty acids are key metabolic substances that provide the brain with signals regarding the body's energy status.

When these substances are available in the bloodstream, they can influence the hypothalamus to adjust the signals related to hunger, which typically leads to a decrease in satiety. Specifically, the presence of free fatty acids can signal the body that energy reserves are sufficient, promoting the feeling of hunger rather than satiety. This indicates that the body requires more food intake to maintain energy balance.

In contrast, substances that enhance satiety would typically signal the brain to reduce food intake after a meal. Therefore, the correct understanding of the relationship between these metabolic markers and the hypothalamus supports the notion that they contribute to a decrease in satiety, ultimately prompting the sensation of hunger rather than fullness.