Which vitamin is crucial for the synthesis of collagen in the human body?

Vitamin C is essential for the synthesis of collagen in the human body. Collagen is a key structural protein found in connective tissues, skin, tendons, and ligaments. Vitamin C plays a significant role in facilitating the hydroxylation of proline and lysine residues in collagen, which is necessary for the stability and integrity of the collagen triple helix structure. Without adequate Vitamin C, the collagen produced is weak and poorly formed, leading to issues such as delayed wound healing and a higher propensity for bruising.

In contrast, while Vitamin A contributes to normal cellular function and is vital for vision, its role is not specific to collagen synthesis. Vitamin D is important for bone health and calcium absorption but does not directly influence collagen production. Vitamin E primarily acts as an antioxidant and protects cell membranes from oxidative stress, not specifically involved in collagen synthesis. Therefore, the critical role of Vitamin C in collagen formation establishes its importance in maintaining healthy connective tissues and overall skin integrity.